Antidepressant
drugs may have an effect on the immune system. Drugs such as Prozac and
Zoloft, which belong to a class known as selective serotonin reuptake
inhibitors, or "SSRIs," work by making the chemical serotonin
remain for longer periods at nerve junctions.
New research indicates that serotonin is also a signaling molecule between
immune cells. Dendritic cells pick up serotonin at inflammation sites and
pass it along to T cells. This affects T cell growth and division into new
cells.
However, when Prozac was introduced at inflammation sites,
it blocked this type of serotonin uptake.
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